| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |


What is CAS 113274-56-9 Hirudin Powder?
| Product Name: | HIRUDIN (54-65) (DESULFATED) |
| CAS: | 113274-56-9 |
| MF: | C66H93N13O25 |
| MW: | 1468.52 |
| Categories: | API; Hirudin Fragments; Miscellaneous Peptides; Peptides for Cell Biology |
Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property. This is fundamental for the leeches' alimentary habit of hematophagy, since it keeps the blood flowing after the initial phlebotomy performed by the worm on the host's skin.
1. Hirudin is a very promising kind of anticoagulant medicine.
2. Hirudin can be used to treat various thrombus diseases, especially the treatment of venous thrombosis and diffuse blood vessel coagulation.
3. Hirudin can also play a role in the treatment of tumor. It can prevent the metastasis of tumor cells, and has been proved to be effective in tumors such as fibrosarcoma, osteosarcoma, angiosarcoma, melanoma and leukemia.
Hirudin is the strongest thrombin retarder so far. It fuses with thrombin to produce a non-covalent synthase with a dissociation constant of the order of 10-12 and a very fast reaction rate. Hirudin and thrombin have strong infectivity, 1μg can neutralize 5μg thrombin, and the molar ratio is 1:1.
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